Immune Mediators of Rotavirus Antigenemia Clearance in Mice
نویسندگان
چکیده
منابع مشابه
Exosomes: Mediators of Immune Regulation
Extracellular Vesicles, including exosomes, are small membrane fragments released from many cell types, like Mesenchymal Stem Cells (MSCs). They were recognized as a mechanism of intercellular communication. They can transfer proteins, lipids and nucleic acids to other cells. Thus, they have many physiological (angiogenesis, coagulation and tissue repair, etc.) and pathological (e.g. in autoimm...
متن کاملAntigenemia and cytokine expression in rotavirus gastroenteritis in children.
BACKGROUND Antigenemia is commonly found in children with rotavirus infection, although its clinical significance is undetermined. The aim of this study was to evaluate the association of antigenemia with clinical manifestations and cytokine profiles in children infected by rotavirus. METHODS In total, 68 children hospitalized with rotavirus gastroenteritis were enrolled. Serum samples were c...
متن کاملAnalysis of rotavirus antigenemia and extraintestinal manifestations in children with rotavirus gastroenteritis.
OBJECTIVE This study was conducted to examine the association between rotavirus antigenemia and clinical features, particularly extraintestinal manifestations, and the association between serum cytokine levels and rotavirus antigen quantity. METHODS Sixty hospitalized children who received a diagnosis of acute rotavirus gastroenteritis were enrolled in this study. Paired serum samples were co...
متن کاملRotavirus Antigenemia in Children Is Associated with Viremia
BACKGROUND Antigenemia is commonly detected in rotavirus-infected children. Although rotavirus RNA has been detected in serum, definitive proof of rotavirus viremia has not been shown. We aimed to analyze a defined patient population to determine if infectious virus could be detected in sera from children with rotavirus antigenemia. METHODS AND FINDINGS Serum samples obtained upon hospitaliza...
متن کاملQuantification of systemic and local immune responses to individual rotavirus proteins during rotavirus infection in mice.
The purpose of the present study was to develop a quantitative assay that could be used to measure the local and systemic immune responses to specific rotavirus proteins following rotavirus infection of adult mice. To measure these responses, we used an immunocytochemical staining assay of Spodoptera frugiperda (Sf-9) cells which were infected with recombinant baculovirus expressing selected ro...
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ژورنال
عنوان ژورنال: Journal of Virology
سال: 2011
ISSN: 0022-538X
DOI: 10.1128/jvi.00844-10